NEW FACTS ON BROMELAIN. Bromelain, also known as bromelin, is a protein digesting enzyme (protease) extracted from the stump or root portion of the pineapple plant. It is commonly used in Germany for treatment of athletic injury or surgery. There is currently great interest in bromelain research in Germany.
Bromelain blocks 2 pathways of essential fatty acid metabolism – the COX 2 pathway and the LOX pathway. Both of these pathways lead to chronic inflammation. Bromelain does not block the COX 1 pathway which promotes decreased platelet clumping and therefore decreases blood clots.
A similar drug called Licofelone developed in Germany was expected to be a blockbuster but was shown to cause kidney toxicity. It also would have blocked COX 2/LOX pathways without blocking COX 1.
Therefore Bromase is one of the only two drugs we have found which does the anti-inflammatory job safely, and it has shown almost no toxicity except in massive doses which no one could even swallow in a day. Thus there is a wide margin of safety
Bromelain is thought to help maintain healthy cardiac tissue by preventing mild infection or inflammation caused by fatty substances inside the coronary blood vessels where plaque may form. Bromase brand of bromelain reduces inflammation by digesting the byproducts of tissue repair. It reduces mucous, painful ribs, asthma, hay fever, and symptoms of the common cold or influenza. Dosage may be adjusted by following the resting pulse rate, which rises proportionately with increasing dosage.
