A score and seven years ago two brilliant Australian scientists, Drs. Barry Marshall and Robin Warren, brought forth on that continent a new concept dedicated to the proposition that peptic ulcer disease and gastric cancer are infectious in nature, transmissible from person to person by close contact, and are caused by a ubiquitous bacterium named Helicobacter pylori.For this work, they shared the Nobel Prize for Medicine in 2005.
We are now engaged in a worldwide struggle testing whether that idea or any idea so conceived and so dedicated can long endure.
Helicobacter is an omnipresent bacterium commonly found in the intestine, a fact that has made it almost invisible to researchers throughout the world, including, I am embarrassed to say, myself.
But in a larger sense rather it is for us the scientists of the twenty-first century to be dedicated to the great task remaining before us – that we take increased devotion to the cause to which Marshall and Warren were devoted – that we highly resolve that Helicobacter research will have a new birth and shall not perish from the earth.
Hepatitis B vaccine (Recombivax by Merck) has been available since 1986.The hypothesis that I present is that this vaccine, along with other measures as described in The Bannost Plan, can prevent or treat multiple autoimmune diseases actually caused by Helicobacter including obesity, Alzheimer’s disease, metabolic syndrome, diabetes mellitus, and multiple sclerosis, and also can prevent multiple types of adenocarcinoma, including breast, stomach, colon, and prostate by improving the body’s immune response against Helicobacter.
Therefore I have administered this vaccine and started the Plan on a type II diabetic, a type I diabetic of 34 years, a patient with biopsy proven infiltrating duct cell breast cancer who refuses breast surgery and radiation recommended by her doctors, a second patient with biopsy proven breast cancer, and a patient who has had multiple sclerosis for twenty years.The diabetics are responding, one breast cancer patient’s malignancy has disappeared as measured by CAT and PET scans, and the multiple sclerosis patient is walking after years in a wheelchair.These results should encourage others to proceed with blinded studies, which I am unable to finance myself, pursuing this approach.The fate of mankind may depend on the outcome.
At the present time there is much more emphasis, and hence research spending, on cell replacement and development (i.e., stem cell research) than on cell death, which may prove to be just as important or more so.
It is generally accepted that cell death is the consequence of either a passive, degenerative process called necrosis or of an active process called apoptosis.Apoptosis is a complex process that is described as programmed cell death actively driven by the cell.Necrosis is a passive consequence of gross injury to the cell.The physiologic consequences of necrosis are very different than those of apoptosis and have vastly different implications for our health.
According to this hypothesis the causative agent for both autoimmune disease and cancer is Helicobacter pylori.In the case of autoimmune disease, the human body responds to the invasion of this bacterium by initiating cell death via apoptosis in the infected organ.Cells in this organ begin to die.These cells extrude fragments of nucleoli from the cell nucleus which are known as prions and are sequences of amino acids which the immune system recognizes as dangerous.The immune system continues to respond to danger signals, becoming more and more efficient with each cycle.Re-infection occurs repeatedly, as the source of infection continues to recur or the Helicobacter walls itself off and persists.
In the case of cancer, Helicobacter infection or re-infection elicits a different chain of events resulting in cell death by necrosis.No prions are extruded, the organism either is not completely eradicated by the immune system, or is reintroduced by re-infection, and the body responds less and less to its presence or reintroduction.Finally, infected cells lose the capacity to control cell reproduction leading to a wild over-proliferation of this cell population.The body loses the ability to recognize the cells as dangerous and to trigger T cell response.
Killer T Lymphocytes kill the Helicobacter cells to which they are attached.Reduction or dysfunction of these white blood cells results in a failure of chemotaxis:
1. Apoptosis, in which the nucleoli are fragmented and extruded. These extruded fragments are
sequences of amino acids known as prions. The prions send danger signals to the immune
system which restarts the cycle.
2. Necrosis, whereby dead cells are engulfed by macrophages.
These drugs are readily available in the United States with the exception of Acomplia which has not yet been released in this country but is available on the Internet.Therefore Phase I clinical studies of this hypotheses could be begun immediately either alone or in conjunction with standard cancer therapies such as surgery, radiation, and/or chemotherapy following comparison of cure rates without jeopardy to the patients in the trials.
REFERENCES
1. The Gettysburg Address - Speech by Abraham Lincoln, Gettysburg, Pennsylvania, November 19, 1863
2. Recombivax HB® Hepatitis B Vaccine (Recombinant) - Merck & Co., Inc., Whitehouse Station, NJ 08889, USA, Issued October 2006
6. Plague Time “The Prepared Mind,” (Chapter Fifteen) – Paul W. Ewald, Anchor Books, Copyright 2000, 2002
7. “A Better Way for a Cancer Cell to Die,” R. A. Lake and R. G. van der Most, New England Journal of Medicine 2006, 354:2503-2504, June 8, 2006
8. Use It or Lose It – Garth Gilmore and Peter Snell, Ph.D., Department of Internal Medicine at UT Southwestern Medical School, Dallas, Texas
9. Patent Application 10/946,213 - John R. Woodward, M.D. – Department of OB-GYN, UT Southwestern Medical School, Dallas, Texas
10. Essential Fatty Acid Metabolism, Peter Snell, John Woodward (unpublished)
11. “The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control,” Essays Biochem. 2006; 42:105-17-Pedersen, BK.
12. The China Study – Startling Implications for Diet, Weight Loss and Long-term Health – T.Colin Campbell, Ph.D. and Thomas M. Campbell, II
13. “DHEA therapy for women: effect on sexual function and wellbeing,” M. Panjari and Susan R. Davis, Human Reproduction Update Advance Access originally published online on January 5, 2007, Human Reproduction Up-date, pp. 1-10, 2007; doi:10.1093/humupd/dm1055
14. “Serum levels of tumor necrosis factor-alpha, interleukin-6 and interleukin-8 are not increased in dyspeptic patients with Helicobacter pylori-associated gastritis,” Taner Bayraktaroğl, Ahmet Sukru Aras, Selim Aydemir, Can Davutoğlu, Yucel Ustundağ, Hulusi Atmaca, and Ali Borazan, Department of Intern al Medicine, Faculty of Medicine, Zonguldak Karaelmas University, Zanguldak, Turkey, Mediators Inflamm.2004 February; 13(1): 25-28.doi: 10.1080/096293504100016645.
15. Clinical Pharmacology OnHand, Version 2.20, November 2007
16. Plague Time, “The Prepared Mind” (Chapter Fifteen) – Paul W. Ewald, First Anchor Books Edition, Copyright 2000, 2002
17. “More Evidence That Fish Oil Inhibits Breast Cancer,” Vital Choices, Monday, September 5, 2005, Issue 39, Volume 2
18. “Opposing effects of dietary n-3 and n-6 fatty acids on mammary carcinogenesis: The Singapore Chinese Health Study” – Gago-Dominguez M, Yuan JM, Sun CL, Lee HP, Yu MC, BR J Cancer. 2003 Nov 3;89 (9): 1686-92
19. “Lab Rat?” – Geeta Anand, The Wall Street Journal, Weekend Edition, Vol. CCL No. 141, Saturday/Sunday, December 15-16, 2007
20. “Helicobacter species in cancers of the gallbladder and extrahepatic biliary tract” – British Journal of Cancer (2009) 100, 194-199. doi:10.1038/sj.bjc.66047
INSTRUCTIONS FOR BANNOST COCKTAIL
Available without a prescription:
Topical DHEA Cream 50 mg 1 cc daily
Compounded by mixing: ½ DHEA cream (available as Twist 25, brochure in office)
½ Lasting Touch massage lotion (health food store)
Gamma Linoleic Acid 300 mg 1 cap twice a day
Bromase™ (bromelain) 500 mg 3 caps twice a day
Pycnogenol 100 mg 2 caps twice a day
Co-enzyme Q10 100 mg 1 cap twice a day
Selenium 200 mcg 1 cap daily
Resveratrol 250 mgm 1 cap twice a day
Lycopene 30 mgm 1 cap twice a day
NOTE: Other than DHEA cream, all non-prescription items are available at Roy’s Nutrition Center located at the northeast corner Preston Road and Royal Lane (214-987-0213).
Prescription Medications:
Aldara Cream (Imiquimod is 5% cream 1 packet daily, rotating sites (mix with equal
the compounded generic) part of Lasting Touch, separate from DHEA,
for better absorption).
Niaspan (niacin) 500 mg 1 daily at bedtime; if severe flushing and itching
occur, take 2 Tylenol, Actonol, or aspirin 30 min.
to prior to taking Niaspan. If itching continues or
is uncomfortable, take 25 mg Benedryl.)
Lovaza (fish oil) 1 gram 4 caps twice a day
Acomplia (rimonabant) 20 mg 1 tab daily (not currently available in the U.S.)
Take it at your own risk; can double the risk of
suicide according to several studies.
Hepatitis B vaccine (Recombivax) Once a month for three months, then booster 6
(six) months later. Available through the office.
After being on Bannost Cocktail for one month, take the following Rx for two (2) weeks along with Bannost Cocktail:
